Isaac Ellmen

SABS CDT Student

About Me

BMath, University of Waterloo (2019)

MSc, University of Waterloo (2022)

Research Interests

Antibodies work by binding to their targets (antigens), and either inhibiting their function or activating other components of the immune system. Predicting the mode by which an antibody binds to its cognate antigen is called antibody-antigen complex modelling or docking. While general protein complex prediction has seen great improvements in recent years, driven by methods such as AlphaFold Multimer, antibody-antigen complexes are still difficult to model because we rarely have useful homologs to provide co-evolutionary information. My DPhil project is focused on developing new machine learning docking models to more accurately predict antibody-antigen complexes.

Contact Details

Email: isaac.ellmen@stats.ox.ac.uk

Office: 2.19

Pronouns: he/him

Research Groups

Supervisor(s)

Henriette Capel

SABS CDT Student

About Me

I'm a PhD student within the Oxford Protein Informatics Group (OPIG), studying the developability of antibodies. I started my PhD in 2022 through the SABS CDT program. Before this, I completed my Bachelors in Medical Natural Science and Masters in Bioinformatics at the Vrije Universiteit Amsterdam. 

Research Interests

My research focuses on leveraging computational methods to predict antibody developability properties. The goal is to improve efficiency of the antibody engineering and developability process.

Contact Details

Email: henriette.capel@stats.ox.ac.uk

Office: 2.19

Pronouns (optional): She/Her

Research Groups

Oxford Protein Informatics Group

Supervisor(s)

Yael Ziv

DPhil in Statistics student

About Me

Hello! I'm Yael, a DPhil student at the Oxford Protein Informatics Group (OPIG). I'm currently researching structure-based drug design, with a focus on deep-learning generative models. I earned my Bachelor's and Master's degrees in Electrical and Computer Engineering from the Ben-Gurion University in Israel. Outside of academia, I enjoy hiking and exploring the UK with my husband, Gal, and our one-year-old daughter, Abigail.

Research Interests

Deep learning for drug design, graph neural network, generative models

Contact Details

Email: yael.ziv@new.ox.ac.uk

Office: 2.17

Pronouns: She/Her

Supervisors

Prof Charlotte Deane

Prof Brian Marsden

Leo Zhang

StatML CDT student

About Me

I am a second-year DPhil student on the StatML CDT. Previously, I obtained my BSc in Mathematics at Imperial College London and my MSc in Statistical Science at the University of Oxford.

Research Interests

My current research interests include developing meta-learning methods for efficiently adapting LLMs and applications of geometry within machine learning (e.g. deep generative models for manifold-valued data and geometric deep learning). I am also increasingly interested in the intersection of cognitive science and neuroscience with machine learning, for inspiring more effective and efficient learning algorithms.

Contact Details

Email: leo.zhang@stx.ox.ac.uk

Website: Leo Zhang

Office: G.05

Pronouns: He/Him

Supervisor

Leo Tyrpak

DPhil in Statistics student

About Me

I am a 2nd year DPhil student in the probability group in the statistics department.

I did my MMath in Oxford.

Research Interests

Modelling biological processes, specifically in the area of population genetics

Contact Details

Email: leo.tyrpak@stats.ox.ac.uk

Office: 3.01

Pronouns: He/Him

Groups

Probability group

Peter Potaptchik

StatML CDT student

About Me

I am a second-year DPhil student at Oxford and part of the StatML CDT. Previously, I completed a BSc in Computer Science and Statistics at the University of Toronto.

 

Research Interests

My research centers on generative modelling and sampling, with a focus on bridging various fields. I’m particularly interested in using techniques from differential geometry, optimal transport, probability, and statistical learning theory to deepen our understanding of the strengths and limitations of algorithms in these areas. I also have a broader interest in machine learning theory.

Contact Details

Email: peter.potaptchik@stats.ox.ac.uk

Office: G.05

Pronouns (optional): He/Him

Sam Money-Kyrle

DPhil in Statistics student

About Me

Hello! My name is Sam, and I am a first-year DPhil student in Statistics. I work in the Oxford Protein Informatics Group (OPIG), where I research machine learning applications for small molecule drug discovery. I am funded via an EPSRC CASE conversion studentship in collaboration with Lhasa Limited. I hold an MSc in Bioinformatics from Imperial College London and a BSc in Biochemistry from the University of Edinburgh.

Research Interests

  • Structural bioinformatics.
  • Machine learning for drug discovery.

Contact Details

Office: G.05

Pronouns: He/Him

Sitong Liu

DPhil in Statistics student

About Me

I am a first-year Dphil student in Statistics supervised by Prof. Geoff Nicholls and Dr. Chieh-Hsi Wu (from University of Southampton). Before joining Oxford, I obtained my bachelor's degree in Statistical Science at the University of Hong Kong, Shenzhen , and during my third year of undergraduate study, I spent a wonderful time at Oxford as a visiting student. Nice to be back!

My current research interest focuses on Bayesian statistics, especially Bayesian model misspecification. On my way to explore new knowledge and extend my interest!

Research Interests

Bayesian statistics

Contact Details

Email: sitong.liu@spc.ox.ac.uk

Office:

Pronouns: She/ Her

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