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Breadcrumb
DPhil in Statistics student
About Me
I completed my Integrated Master's (MChem) in Medicinal and Biological Chemistry at the University of Edinburgh. In my final year, I worked at AstraZeneca in oncology computational chemistry, contributing to small molecule drug discovery projects. There, I gained experience developing and applying AI methods to support drug discovery efforts.
Research Interests
My research focuses on developing artificial intelligence methods for small molecule drug discovery. The ultimate aim is to create tools that accelerate the discovery and development of novel medicines, addressing unmet medical needs more efficiently, cost-effectively, and with improved outcomes.
Currently, my research is centered around the application of large language models (such as ChatGPT, Claude, Gemini, etc.) in chemistry. I investigate whether these models truly "understand" chemistry and their potential to significantly aid scientific discovery. In particular, I am exploring how these models can leverage chemical theory to generate new hypotheses, design experiments, and interpret experimental results.
My first preprint as part of the Oxford Protein Informatics Group (OPIG) examines the ability of the latest large language models (known as reasoning models) to interpret molecular structures. Our findings demonstrate that these models can successfully perform highly complex chemistry tasks.
Selected publications:
- Assessing the Chemical Intelligence of Large Language Models (preprint available on arXiv: https://arxiv.org/abs/2505.07735)
- SILVR: Guided Diffusion for Molecule Generation (Journal of Chemical Information and Modeling, https://pubs.acs.org/doi/full/10.1021/acs.jcim.3c00667)
Contact Details
Email: runcie@stats.ox.ac.uk
Office: 2.11
Pronouns: He/Him
Research Groups
Supervisor
Breadcrumb
Postdoctoral Researcher
About Me
I am a postdoctoral researcher working with Dr. Duncan Palmer, continuing work from my DPhil involving the study of individuals with genetically-unexpected phenotypes in the UK Biobank. I was a DPhil student in the Genomic Medicine and Statistics programme run by the Wellcome Centre for Human Genetics, with my thesis co-supervised by Prof. Cecilia Lindgren and Prof. Simon Myers. Prior to Oxford, I graduated from Brown University with a degree in applied mathematics and worked for two years in the Neale Lab at the Broad Institute of MIT and Harvard.
Research Interests
Complex disease, polygenic scores, obesity, outliers, biomarkers, genome/exome-wide association studies, rare variant burden
Publications
Contact Details
Email: nikolas.baya@pmb.ox.ac.uk
Office: Big Data Institute
Pronouns: He/Him
Research Groups
Groups: Lindgren/Palmer
Breadcrumb
DPhil in Statistics student
About Me
I am a first-year DPhil student in the Department of Statistics and the Pandemic Science Institute at the University of Oxford. I completed my MSc in Modelling for Global Health (2023/2024) at Oxford and hold a BSc in Economics and Statistics (2020-2023) from University College London, where I developed a strong interest in statistical modeling and public health. My current research focuses on using mathematical tools to better understand mosquito-borne diseases and to inform more effective vector control strategies. Additionally, I am involved in a project that applies statistical analysis and software development to interpret serological data. My work integrates advanced statistical methods, mathematical modeling, and computational techniques to better understand disease transmission and contribute to public health strategies.
Research Interests
- Mosquito-borne diseases
- Mathematical biology
- Serological data analysis
- Statistical inference and Software development for infectious disease modelling
- Public health applications, e.g., vaccine immunology
Contact Details
junjie.chen@stats.ox.ac.uk