I am a SMARTbiomed Senior Research Fellow, jointly based at the Big Data Institute (BDI) and the Department of Statistics. I co-lead the Biobank Rare-Variant Consortium (BRaVa), a collaborative effort involving 16 biobanks and cohorts (to date) from around the world to analyse rare genetic variation at scale to identify the genetic underpinnings of complex traits and disorders. I also co-lead the (gen)omics theme at the BDI.

I received an integrated master's degree in Mathematics and Statistics from the University of Warwick and a DPhil in Statistics from the University of Oxford, supervised by Professor Dame Angela McLean and Professor Gil McVean. I subsequently worked as a postdoctoral researcher with Professor Ben Neale, Dr Nick Patterson, and Professor Cecilia Lindgren at Massachusetts General Hospital, the Broad Institute, and the University of Oxford.

I develop and apply statistical and computational methods to gain insight into disease mechanisms. I am particularly interested in combining genetic, phenotypic and functional data to better refine association signals and understand the genetic architecture of complex traits. To this end, I collaborate with international partners to assemble and analyse large public datasets of human genetic variation.

As genetic sequencing datasets continue to grow, the tools we use must grow with them. My work also focuses on building scalable methods and computational approaches to analyse massive genetic datasets.