At this year's meeting of the 2018 Intelligent Systems for Molecular Biology (ISMB) Conference, the award went to Fergus Boyles for Learning from the ligand: improving binding affinity prediction using molecular descriptors (Fergus Boyles, Charlotte Deane, Garrett Morris, University of Oxford, United Kingdom). Many thanks to Co-Chairs Casey Greene (University of Pennsylvania) and Arjun Krishnan (Michigan State University), and Steven Leard (ISMB).