Guy Durant

SABS CDT Student

About Me

I am a 2nd year DPhil student in the Department of Statistics funded by the Engineering and Physical Sciences Research Council (EPSRC). I am currently researching the impact of structural data drift on deep leaning scoring functions, algorithms that predict a binding affinity between a protein and a small chemical compound or drug. I have a strong interest in the role of protein flexibility in small molecule drug design and wish to incorporate this information into biological models of drug binding. I have an integrated undergraduate masters degree in Biochemistry from the University of Oxford (2021).

Research Interests

Small molecule drug design Deep learning approaches to predicting protein-drug dynamics Structural deep learning prediction tools and how they help inform us of protein dynamics

Contact Details

Email: guy.durant@linacre.ox.ac.uk

Office: 2.11

Supervisors

Dr Fergus Boyles

Prof Brian Marsden

Prof Charlotte Deane