Associate Professor of Systems Approaches to Biomedicine
He began as an Oxford undergraduate Chemist, completing his Part II and DPhil with W. Graham Richards; in 1991 he moved to The Scripps Research Institute, California, to work on protein-ligand docking and AutoDock, and in 2000 launched the first biomedical volunteer computing project, FightAIDS@Home, which helped spawn other biomedical projects with IBM’s World Community Grid. He moved back the UK in 2008 to work in the Oxford spinout, InhibOx, doing ‘real-world drug discovery, where he spearheaded the use of cloud computing; and then to Crysalin, another Oxford spinout, to develop novel protein engineering techniques for protein crystallization. He is now an Associate Professor and works closely with Prof. Deane in the Department of Statistics. Like Charlotte, he is also Programme Co-Director for the EPSRC & MRC SABS CDT (Systems Approaches to Biomedical Science Centre for Doctoral Training).
Methods development in computer-aided drug discovery, chiefly in high throughput docking, ligand-based virtual screening, network pharmacology, cheminfomatics, bioinformatics, machine learning and more recently protein engineering.