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Dr Matthew Raybould
Research Fellow


 

About Me

I’m currently a Research Fellow in immunoinformatics working in the Oxford Protein Informatics Group. Outside Statistics, I am Director of the Open-Innovation Industrial Consortium (Open-IIC), co-director of the ILESLA and TTPS DPhil Programmes, and a Lecturer of Biochemistry at Merton College.

Background

2026-Present: Research Fellow in Immunoinformatics, Oxford Protein Informatics Group
2021-2026: Postdoctoral Researcher in Immunoinformatics, Oxford Protein Informatics Group
2020-2021: Postdoctoral Research Assistant in Immunoinformatics, Oxford Protein Informatics Group
2016-2020: DPhil in Immunoinformatics, Oxford Protein Informatics Group (New College)
2012-2016: MChem in Chemistry (University of Oxford, Merton College)

Research Interests

Analysing datasets of B-cell/antibody/T-cell sequences and structures to better characterise the adaptive immune system, improving our understanding of pathogen responses, immunosenesence, immunodeficiency, autoimmunity, allergy, and cancer. I’m particularly motivated to translate the lessons we learn to the design of novel diagnostics and therapeutics that improve patient outcomes.

Publications

Schneider, C., Raybould, M. and Deane, C. (2021) “SAbDab in the age of biotherapeutics: updates including SAbDab-nano, the nanobody structure tracker”, Nucleic Acids Research, 50(D1), pp. D1368 - D1372.
Raybould, M., Rees, A. and Deane, C. (2021) “Current strategies for detecting functional convergence across B-cell receptor repertoires”, mAbs, 13(1).
Robinson, S. et al. (2021) “Epitope profiling of coronavirus-binding antibodies using computational structural modelling.”
Raybould, M. et al. (2021) “Public Baseline and shared response structures support the theory of antibody repertoire functional commonality”, PLOS Computational Biology, 17(3).
Galson, J. et al. (2020) “Deep sequencing of B cell receptor repertoires from COVID-19 patients reveals strong convergent immune signatures”, Frontiers in Immunology, 11.
Raybould, M. et al. (2020) “CoV-AbDab: the coronavirus antibody database”, Bioinformatics, 37(5), pp. 734–735.
Raybould, M. et al. (2020) “CoV-AbDab: the Coronavirus Antibody Database”, p. 2020.05.15.077313.
Raybould, M. et al. (2020) “Evidence of Antibody Repertoire Functional Convergence through Public Baseline and Shared Response Structures”, p. 2020.03.17.993444.
Kovaltsuk, A. et al. (2020) “Structural diversity of B-cell receptor repertoires along the B-cell differentiation axis in humans and mice”, PLOS Computational Biology, 16(2).
Galson, J. et al. (2020) “Deep sequencing of B cell receptor repertoires from COVID-19 patients reveals strong convergent immune signatures”, bioRxiv.

Contact Details

Email: matthew.raybould@stats.ox.ac.uk

Office: 2.04