Evolving Dynamical Systems – case study: Cell Cycle
The biosciences has recently seen the rise of two major trends. Firstly, the use of evolution in structural biology as seen in bioinformatics and comparative genomics. Secondly, the use of predictive mathematical modelling in systems biology and computational biology. Clearly, there is an intersection between these two major areas and it would belong to the field of comparative systems biology. We will here simplify fast to get to a simple well-defined problem. Two phylogenetically related dynamical systems used to describe two homologous biological systems. Such a relationship could place constraints on which kinds of models you could use. Very often you demand certain kinds of stability of the model and now you would have to demand that all ancestral intermediates are also stable. This could place constraints on which order you could remove/add/modify components.