SEBASTIAN KELM

I am a member of the Oxford Protein Informatics Group, led by Prof Charlotte Deane, at Oxford University's Department of Statistics. My formal education is in Biochemistry as well as Bioinformatics and Systems Biology, which I studied at Imperial College London. I did my DPhil degree here, in the Protein Informatics Group, on the topic of "Structural Prediction of Transmembrane Domains". As a post-doc I now work with Charlotte Deane, Frank von Delft (at the Structural Genomics Consortium) and other collaborators on predicting membrane protein complexes. I am funded by the 2020 Science Project, which aims to produce the next generation of computational scientists.

Academic background

NAME Sebastian Kelm | OCCUPATION Research Fellow | INTERESTS Computers, Proteins and Martial Arts

I spend several hours per week learning and teaching martial arts for self-defence. In addition I play football with my colleagues from the Stats department.

When I am not working

Research interests

My current research is focused on the development of methods for structure prediction of membrane proteins complexes. This involves the integration of computational methods (such MEDELLER, iMembrane and PyFREAD) with various kinds of experimental data. My main goal is to be able to predict the static 3d structure of a membrane protein complex and then insert it into a molecular dynamics-type framework to simulate its interaction with other proteins and ligands. Ultimately, this information could then serve to inform higher level models.