* using log directory ‘/data/blackswan/ripley/R/packages/tests-devel/nlmixr.Rcheck’ * using R Under development (unstable) (2022-10-07 r83044) * using platform: x86_64-pc-linux-gnu (64-bit) * using session charset: UTF-8 * checking for file ‘nlmixr/DESCRIPTION’ ... OK * checking extension type ... Package * this is package ‘nlmixr’ version ‘2.0.7’ * package encoding: UTF-8 * checking package namespace information ... OK * checking package dependencies ... OK * checking if this is a source package ... OK * checking if there is a namespace ... OK * checking for executable files ... OK * checking for hidden files and directories ... OK * checking for portable file names ... OK * checking for sufficient/correct file permissions ... OK * checking whether package ‘nlmixr’ can be installed ... [247s/128s] OK * checking package directory ... OK * checking DESCRIPTION meta-information ... OK * checking top-level files ... OK * checking for left-over files ... OK * checking index information ... OK * checking package subdirectories ... OK * checking R files for non-ASCII characters ... OK * checking R files for syntax errors ... OK * checking whether the package can be loaded ... OK * checking whether the package can be loaded with stated dependencies ... OK * checking whether the package can be unloaded cleanly ... OK * checking whether the namespace can be loaded with stated dependencies ... OK * checking whether the namespace can be unloaded cleanly ... OK * checking loading without being on the library search path ... OK * checking dependencies in R code ... OK * checking S3 generic/method consistency ... OK * checking replacement functions ... OK * checking foreign function calls ... OK * checking R code for possible problems ... [44s/44s] OK * checking Rd files ... OK * checking Rd metadata ... OK * checking Rd line widths ... OK * checking Rd cross-references ... OK * checking for missing documentation entries ... OK * checking for code/documentation mismatches ... OK * checking Rd \usage sections ... OK * checking Rd contents ... OK * checking for unstated dependencies in examples ... OK * checking contents of ‘data’ directory ... OK * checking data for non-ASCII characters ... OK * checking LazyData ... OK * checking data for ASCII and uncompressed saves ... OK * checking line endings in shell scripts ... OK * checking line endings in C/C++/Fortran sources/headers ... OK * checking line endings in Makefiles ... OK * checking compilation flags in Makevars ... OK * checking for GNU extensions in Makefiles ... OK * checking for portable use of $(BLAS_LIBS) and $(LAPACK_LIBS) ... OK * checking use of PKG_*FLAGS in Makefiles ... OK * checking use of SHLIB_OPENMP_*FLAGS in Makefiles ... OK * checking compilation flags used ... OK * checking compiled code ... OK * checking examples ... OK * checking examples with --run-donttest ... [16s/16s] ERROR Running examples in ‘nlmixr-Ex.R’ failed The error most likely occurred in: > ### Name: addNpde > ### Title: NPDE calculation for nlmixr > ### Aliases: addNpde > > ### ** Examples > > > ## No test: > > one.cmt <- function() { + ini({ + ## You may label each parameter with a comment + tka <- 0.45 # Log Ka + tcl <- log(c(0, 2.7, 100)) # Log Cl + ## This works with interactive models + ## You may also label the preceding line with label("label text") + tv <- 3.45; label("log V") + ## the label("Label name") works with all models + eta.ka ~ 0.6 + eta.cl ~ 0.3 + eta.v ~ 0.1 + add.sd <- 0.7 + }) + model({ + ka <- exp(tka + eta.ka) + cl <- exp(tcl + eta.cl) + v <- exp(tv + eta.v) + linCmt() ~ add(add.sd) + }) + } > > f <- nlmixr(one.cmt, theo_sd, "saem") ℹ parameter labels from comments are typically ignored in non-interactive mode ℹ Need to run with the source intact to parse comments → generate SAEM model ✔ done make[1]: warning: jobserver unavailable: using -j1. Add '+' to parent make rule. make[1]: warning: jobserver unavailable: using -j1. Add '+' to parent make rule. 1: 0.2305 0.9671 3.4723 0.5700 0.2850 0.0950 4.4919 2: 0.3651 0.9778 3.5295 0.5415 0.2707 0.0902 1.7823 3: 0.4882 0.9147 3.4856 0.5144 0.2572 0.0857 0.9433 4: 0.4388 0.9472 3.4840 0.4887 0.2444 0.0815 0.7109 5: 0.4829 0.9508 3.4741 0.4643 0.2321 0.0774 0.6214 6: 0.4920 0.9792 3.4720 0.4411 0.2205 0.0735 0.5153 7: 0.4777 1.0028 3.4600 0.4269 0.2095 0.0698 0.5071 8: 0.4391 0.9985 3.4583 0.4056 0.1990 0.0663 0.5103 9: 0.4114 0.9775 3.4580 0.3853 0.1891 0.0630 0.5211 10: 0.4107 0.9914 3.4474 0.4237 0.1796 0.0599 0.5031 11: 0.4334 1.0173 3.4396 0.4026 0.1706 0.0569 0.5035 12: 0.4362 1.0233 3.4396 0.3824 0.1621 0.0540 0.4856 13: 0.3955 1.0403 3.4232 0.3633 0.1540 0.0513 0.4968 14: 0.4067 1.0196 3.4387 0.4627 0.1463 0.0488 0.4935 15: 0.4418 1.0214 3.4495 0.4395 0.1390 0.0463 0.4847 16: 0.4555 1.0222 3.4523 0.4272 0.1320 0.0440 0.5063 17: 0.4723 0.9985 3.4633 0.4328 0.1254 0.0418 0.4749 18: 0.4713 0.9710 3.4543 0.4301 0.1192 0.0397 0.5001 19: 0.4586 1.0053 3.4522 0.4213 0.1132 0.0377 0.4762 20: 0.4686 1.0159 3.4491 0.4415 0.1075 0.0358 0.4926 21: 0.4525 1.0063 3.4582 0.4194 0.1022 0.0341 0.4619 22: 0.4383 1.0097 3.4606 0.4134 0.0971 0.0324 0.4611 23: 0.5105 1.0017 3.4695 0.4324 0.0922 0.0307 0.4693 24: 0.4888 1.0081 3.4691 0.4107 0.0876 0.0292 0.4601 25: 0.4573 1.0045 3.4623 0.3902 0.0890 0.0277 0.4746 26: 0.4185 1.0213 3.4423 0.3951 0.0845 0.0264 0.4757 27: 0.4101 1.0423 3.4402 0.3753 0.0803 0.0250 0.5107 28: 0.4670 1.0181 3.4478 0.3566 0.0763 0.0238 0.4552 29: 0.4637 1.0191 3.4483 0.3514 0.0742 0.0226 0.4823 30: 0.4823 1.0191 3.4489 0.3386 0.0743 0.0215 0.4951 31: 0.4069 1.0082 3.4580 0.3217 0.0849 0.0204 0.4833 32: 0.4274 0.9955 3.4673 0.3516 0.0806 0.0194 0.4877 33: 0.4486 1.0011 3.4596 0.3814 0.0766 0.0184 0.5041 34: 0.4835 1.0048 3.4582 0.4096 0.0728 0.0175 0.4855 35: 0.4500 1.0009 3.4576 0.3892 0.0691 0.0166 0.4789 36: 0.4521 1.0192 3.4494 0.3697 0.0690 0.0158 0.4873 37: 0.4443 1.0203 3.4556 0.3676 0.0713 0.0195 0.4830 38: 0.5028 1.0178 3.4465 0.4699 0.0773 0.0186 0.4955 39: 0.4952 0.9817 3.4726 0.4464 0.0735 0.0237 0.4637 40: 0.4771 0.9930 3.4763 0.4241 0.0698 0.0260 0.4682 41: 0.4646 0.9895 3.4716 0.4029 0.0663 0.0247 0.4842 42: 0.4724 1.0117 3.4602 0.3828 0.0748 0.0235 0.4609 43: 0.4411 1.0275 3.4433 0.3636 0.0755 0.0223 0.4672 44: 0.4393 1.0245 3.4456 0.3676 0.0718 0.0212 0.4858 45: 0.4213 1.0442 3.4313 0.3932 0.0682 0.0201 0.4756 46: 0.4131 1.0255 3.4391 0.4216 0.0779 0.0191 0.4802 47: 0.4401 1.0325 3.4398 0.4268 0.0740 0.0181 0.4612 48: 0.4603 1.0197 3.4460 0.4863 0.0726 0.0196 0.4734 49: 0.4523 1.0101 3.4449 0.4619 0.0752 0.0186 0.4863 50: 0.4857 0.9838 3.4442 0.4439 0.0821 0.0178 0.5032 51: 0.4827 1.0036 3.4402 0.4614 0.0890 0.0190 0.5150 52: 0.5207 0.9994 3.4615 0.5074 0.0845 0.0180 0.4780 53: 0.5052 1.0095 3.4547 0.4987 0.0803 0.0171 0.4658 54: 0.4724 1.0147 3.4560 0.4737 0.0763 0.0163 0.4847 55: 0.4456 1.0103 3.4482 0.4500 0.0770 0.0155 0.4727 56: 0.4556 0.9972 3.4503 0.4310 0.0731 0.0180 0.4873 57: 0.4717 0.9961 3.4601 0.4094 0.0695 0.0178 0.5002 58: 0.5111 0.9884 3.4595 0.3906 0.0689 0.0169 0.4843 59: 0.5299 0.9601 3.4775 0.4401 0.0848 0.0160 0.5179 60: 0.5258 0.9706 3.4786 0.4721 0.0806 0.0172 0.5463 61: 0.5476 0.9869 3.4828 0.4989 0.0846 0.0175 0.5335 62: 0.4957 0.9961 3.4819 0.4739 0.0873 0.0197 0.5230 63: 0.5010 0.9844 3.4750 0.4502 0.0868 0.0211 0.4994 64: 0.4980 0.9863 3.4719 0.4594 0.0856 0.0201 0.5006 65: 0.4999 0.9879 3.4558 0.4840 0.0902 0.0191 0.4858 66: 0.4855 1.0094 3.4708 0.4598 0.0965 0.0181 0.4656 67: 0.4799 0.9869 3.4526 0.4368 0.0917 0.0172 0.4720 68: 0.4261 1.0070 3.4548 0.4150 0.0871 0.0163 0.5139 69: 0.4372 1.0071 3.4479 0.4108 0.0827 0.0155 0.5039 70: 0.4523 1.0070 3.4606 0.4929 0.0786 0.0156 0.5108 71: 0.4312 1.0303 3.4359 0.4682 0.0770 0.0181 0.5383 72: 0.4553 0.9787 3.4556 0.4448 0.0749 0.0172 0.4921 73: 0.4797 1.0105 3.4687 0.4226 0.0749 0.0163 0.4876 74: 0.4795 1.0006 3.4598 0.4014 0.0712 0.0155 0.4624 75: 0.5021 0.9811 3.4820 0.4242 0.0778 0.0187 0.4671 76: 0.5250 1.0031 3.4901 0.4030 0.0739 0.0192 0.4885 77: 0.5216 0.9688 3.4883 0.4116 0.0702 0.0199 0.5193 78: 0.5108 0.9865 3.4845 0.4293 0.0756 0.0221 0.4785 79: 0.5097 0.9947 3.4755 0.4346 0.0718 0.0254 0.5220 80: 0.5230 0.9928 3.4795 0.4593 0.0682 0.0265 0.5049 81: 0.5519 0.9995 3.4804 0.4364 0.0648 0.0272 0.4777 82: 0.5369 0.9764 3.4881 0.4180 0.0616 0.0258 0.4909 83: 0.5110 0.9914 3.4757 0.4266 0.0585 0.0245 0.4752 84: 0.4835 0.9822 3.4678 0.4053 0.0630 0.0233 0.4759 85: 0.4943 1.0028 3.4816 0.3851 0.0631 0.0221 0.4854 86: 0.4739 1.0058 3.4669 0.3658 0.0737 0.0210 0.4683 87: 0.4323 1.0174 3.4464 0.3475 0.0727 0.0200 0.4687 88: 0.3573 1.0096 3.4444 0.3565 0.0739 0.0190 0.5053 89: 0.4307 1.0124 3.4422 0.3416 0.0705 0.0180 0.5228 90: 0.3981 1.0268 3.4291 0.3703 0.0670 0.0171 0.5147 91: 0.4057 1.0303 3.4166 0.4033 0.0742 0.0183 0.5056 92: 0.4643 1.0388 3.4407 0.4198 0.0922 0.0214 0.5000 93: 0.3853 1.0218 3.4418 0.3988 0.0876 0.0203 0.4876 94: 0.4144 1.0191 3.4380 0.3871 0.0971 0.0193 0.5084 95: 0.4261 1.0446 3.4388 0.4601 0.0923 0.0184 0.4936 96: 0.4135 1.0207 3.4357 0.4725 0.0877 0.0183 0.4864 97: 0.4439 1.0279 3.4522 0.4489 0.0833 0.0181 0.4938 98: 0.4766 1.0194 3.4610 0.4265 0.0791 0.0172 0.4916 99: 0.4605 0.9854 3.4526 0.4580 0.0752 0.0164 0.4765 100: 0.4330 0.9965 3.4527 0.4351 0.0714 0.0163 0.4743 101: 0.3980 1.0110 3.4321 0.4134 0.0747 0.0170 0.4516 102: 0.4152 1.0176 3.4287 0.3927 0.0710 0.0185 0.4891 103: 0.4471 1.0166 3.4446 0.4006 0.0689 0.0192 0.4586 104: 0.4308 1.0155 3.4490 0.4306 0.0654 0.0183 0.4998 105: 0.4187 0.9930 3.4461 0.4091 0.0808 0.0174 0.5012 106: 0.4735 0.9846 3.4557 0.4018 0.0812 0.0165 0.4898 107: 0.5128 1.0054 3.4604 0.4465 0.0885 0.0157 0.4790 108: 0.4794 0.9893 3.4599 0.4242 0.0841 0.0149 0.5088 109: 0.4480 0.9997 3.4670 0.4030 0.0866 0.0160 0.4887 110: 0.4750 1.0124 3.4507 0.3828 0.0823 0.0167 0.4980 111: 0.4563 1.0069 3.4587 0.3637 0.0790 0.0160 0.4819 112: 0.4692 0.9962 3.4481 0.3649 0.0770 0.0169 0.4872 113: 0.4327 1.0425 3.4484 0.3708 0.0768 0.0161 0.4796 114: 0.4215 1.0422 3.4462 0.3522 0.0953 0.0153 0.4642 115: 0.4546 1.0155 3.4399 0.3469 0.0920 0.0169 0.4788 116: 0.4536 1.0027 3.4477 0.3984 0.0874 0.0190 0.4825 117: 0.4284 1.0386 3.4491 0.3851 0.0859 0.0181 0.4793 118: 0.4485 1.0224 3.4483 0.3658 0.0841 0.0172 0.4807 119: 0.4783 1.0052 3.4558 0.3999 0.0799 0.0216 0.4871 120: 0.4478 0.9837 3.4651 0.4012 0.0759 0.0206 0.4723 121: 0.4564 1.0135 3.4587 0.3812 0.0721 0.0199 0.4664 122: 0.4615 0.9840 3.4500 0.3978 0.0685 0.0197 0.4688 123: 0.5128 1.0198 3.4507 0.4289 0.0715 0.0196 0.4634 124: 0.4910 1.0332 3.4499 0.4603 0.0679 0.0225 0.4727 125: 0.4774 1.0296 3.4479 0.4373 0.0714 0.0214 0.4699 126: 0.4323 1.0446 3.4350 0.4352 0.0782 0.0203 0.4749 127: 0.4545 1.0391 3.4337 0.4134 0.0817 0.0193 0.4959 128: 0.4108 1.0267 3.4404 0.4637 0.0777 0.0229 0.5114 129: 0.4250 1.0351 3.4494 0.4985 0.0762 0.0217 0.4695 130: 0.5269 1.0264 3.4570 0.5079 0.0745 0.0207 0.4488 131: 0.4508 1.0179 3.4401 0.4825 0.0709 0.0196 0.4701 132: 0.4299 1.0122 3.4282 0.4583 0.0734 0.0186 0.5105 133: 0.4165 1.0089 3.4401 0.4354 0.0726 0.0177 0.4845 134: 0.4491 0.9936 3.4602 0.4137 0.0749 0.0197 0.4931 135: 0.4562 0.9995 3.4599 0.3930 0.0796 0.0191 0.4891 136: 0.4833 0.9866 3.4660 0.3733 0.0756 0.0182 0.4804 137: 0.4878 0.9942 3.4615 0.3783 0.0718 0.0173 0.4995 138: 0.4698 1.0094 3.4572 0.4097 0.0682 0.0173 0.4824 139: 0.4838 1.0133 3.4667 0.4908 0.0697 0.0213 0.4688 140: 0.4906 1.0098 3.4702 0.4663 0.0693 0.0202 0.4961 141: 0.4826 0.9823 3.4663 0.4430 0.0727 0.0212 0.4684 142: 0.4752 0.9888 3.4644 0.4208 0.0746 0.0201 0.4767 143: 0.4569 1.0147 3.4593 0.4186 0.0709 0.0208 0.4761 144: 0.4881 1.0258 3.4572 0.3977 0.0676 0.0197 0.4520 145: 0.4463 1.0301 3.4403 0.4076 0.0693 0.0193 0.4448 146: 0.4252 1.0312 3.4518 0.4247 0.0663 0.0189 0.4628 147: 0.4406 1.0123 3.4379 0.4034 0.0695 0.0179 0.4513 148: 0.4028 1.0283 3.4515 0.3863 0.0660 0.0176 0.4600 149: 0.4380 1.0134 3.4537 0.3705 0.0715 0.0195 0.4572 150: 0.4460 1.0115 3.4409 0.3890 0.0695 0.0185 0.4753 151: 0.3816 1.0358 3.4308 0.3696 0.0660 0.0189 0.4664 152: 0.4094 1.0377 3.4363 0.3878 0.0736 0.0205 0.4603 153: 0.4208 1.0246 3.4532 0.3954 0.0651 0.0225 0.4678 154: 0.4760 1.0340 3.4597 0.3910 0.0733 0.0216 0.4652 155: 0.4678 1.0123 3.4597 0.4495 0.0627 0.0242 0.4619 156: 0.4882 1.0151 3.4639 0.4176 0.0778 0.0244 0.4968 157: 0.4449 1.0079 3.4669 0.3499 0.0622 0.0259 0.4942 158: 0.4593 1.0261 3.4542 0.3701 0.0581 0.0261 0.4708 159: 0.4133 1.0247 3.4577 0.3636 0.0523 0.0238 0.5084 160: 0.4843 0.9950 3.4734 0.5106 0.0621 0.0193 0.5039 161: 0.4660 0.9900 3.4651 0.3748 0.0475 0.0230 0.5116 162: 0.4052 1.0211 3.4512 0.4324 0.0512 0.0233 0.5002 163: 0.4668 1.0048 3.4494 0.4723 0.0458 0.0217 0.4768 164: 0.4520 1.0149 3.4540 0.4130 0.0464 0.0243 0.4751 165: 0.4638 1.0211 3.4498 0.3954 0.0483 0.0214 0.4819 166: 0.4716 1.0375 3.4603 0.3928 0.0440 0.0226 0.4920 167: 0.4907 1.0337 3.4710 0.3186 0.0528 0.0252 0.4956 168: 0.4645 1.0322 3.4643 0.3550 0.0579 0.0253 0.4877 169: 0.4779 1.0502 3.4501 0.3294 0.0687 0.0195 0.5175 170: 0.4641 1.0227 3.4524 0.3495 0.0525 0.0207 0.5195 171: 0.4333 1.0251 3.4446 0.3388 0.0605 0.0212 0.4732 172: 0.4484 1.0351 3.4497 0.3383 0.0633 0.0223 0.4638 173: 0.4087 1.0325 3.4342 0.3153 0.0635 0.0287 0.4709 174: 0.4407 1.0396 3.4500 0.3038 0.0544 0.0282 0.4815 175: 0.4513 1.0338 3.4519 0.3305 0.0612 0.0279 0.4849 176: 0.4291 1.0364 3.4646 0.3252 0.0608 0.0211 0.4784 177: 0.4815 1.0242 3.4710 0.4081 0.0677 0.0254 0.4577 178: 0.4585 1.0127 3.4598 0.3493 0.0742 0.0195 0.4455 179: 0.4878 1.0230 3.4559 0.3733 0.0917 0.0161 0.4883 180: 0.4427 1.0317 3.4615 0.2961 0.0775 0.0163 0.5045 181: 0.4472 1.0155 3.4380 0.3325 0.0777 0.0178 0.4870 182: 0.4136 1.0280 3.4362 0.3177 0.0863 0.0171 0.4951 183: 0.4261 1.0369 3.4350 0.3631 0.0744 0.0179 0.4868 184: 0.4362 1.0186 3.4395 0.4078 0.0759 0.0166 0.4679 185: 0.3912 1.0324 3.4332 0.3703 0.0735 0.0181 0.4752 186: 0.3899 1.0500 3.4340 0.3790 0.0719 0.0201 0.4749 187: 0.4471 1.0159 3.4450 0.4073 0.0521 0.0220 0.4523 188: 0.4325 1.0288 3.4478 0.4215 0.0657 0.0185 0.4640 189: 0.4640 1.0269 3.4614 0.4195 0.0620 0.0203 0.4738 190: 0.4584 1.0094 3.4703 0.3284 0.0639 0.0201 0.4751 191: 0.4504 1.0322 3.4554 0.3686 0.0596 0.0199 0.4417 192: 0.4375 1.0286 3.4520 0.3424 0.0682 0.0173 0.4629 193: 0.4613 1.0300 3.4533 0.3388 0.0658 0.0194 0.4628 194: 0.4070 1.0239 3.4385 0.4053 0.0638 0.0137 0.4819 195: 0.4061 1.0279 3.4320 0.4020 0.0572 0.0139 0.4906 196: 0.4134 1.0078 3.4434 0.4239 0.0793 0.0145 0.4803 197: 0.4134 1.0191 3.4626 0.3640 0.0683 0.0177 0.5033 198: 0.4838 0.9943 3.4596 0.4695 0.0774 0.0166 0.4694 199: 0.4656 0.9885 3.4531 0.4601 0.0747 0.0167 0.4767 200: 0.4431 0.9989 3.4501 0.4098 0.0791 0.0215 0.5171 201: 0.4232 0.9965 3.4533 0.3900 0.0763 0.0212 0.5069 202: 0.4189 1.0049 3.4498 0.4047 0.0749 0.0212 0.5113 203: 0.4346 1.0043 3.4487 0.4139 0.0752 0.0218 0.5050 204: 0.4403 1.0008 3.4494 0.4216 0.0734 0.0216 0.5040 205: 0.4392 1.0072 3.4484 0.4205 0.0759 0.0220 0.5018 206: 0.4427 1.0137 3.4478 0.4356 0.0754 0.0219 0.5002 207: 0.4390 1.0159 3.4455 0.4369 0.0735 0.0218 0.4999 208: 0.4385 1.0175 3.4459 0.4269 0.0718 0.0218 0.4970 209: 0.4423 1.0164 3.4454 0.4281 0.0708 0.0217 0.4944 210: 0.4462 1.0153 3.4466 0.4284 0.0700 0.0216 0.4915 211: 0.4509 1.0161 3.4478 0.4295 0.0697 0.0213 0.4892 212: 0.4552 1.0149 3.4486 0.4285 0.0691 0.0209 0.4901 213: 0.4557 1.0115 3.4497 0.4241 0.0690 0.0207 0.4922 214: 0.4617 1.0100 3.4513 0.4254 0.0696 0.0205 0.4926 215: 0.4634 1.0094 3.4530 0.4228 0.0701 0.0205 0.4934 216: 0.4687 1.0070 3.4543 0.4281 0.0702 0.0204 0.4945 217: 0.4699 1.0071 3.4554 0.4298 0.0703 0.0205 0.4940 218: 0.4711 1.0074 3.4555 0.4308 0.0703 0.0204 0.4943 219: 0.4703 1.0069 3.4551 0.4301 0.0699 0.0203 0.4938 220: 0.4677 1.0071 3.4546 0.4263 0.0698 0.0203 0.4938 221: 0.4656 1.0071 3.4544 0.4216 0.0696 0.0203 0.4937 222: 0.4652 1.0073 3.4540 0.4226 0.0696 0.0203 0.4939 223: 0.4665 1.0072 3.4543 0.4236 0.0695 0.0203 0.4927 224: 0.4683 1.0075 3.4547 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0.4159 0.0717 0.0193 0.4851 410: 0.4536 1.0137 3.4506 0.4160 0.0717 0.0193 0.4851 411: 0.4535 1.0136 3.4505 0.4158 0.0717 0.0193 0.4851 412: 0.4534 1.0138 3.4505 0.4154 0.0717 0.0193 0.4852 413: 0.4533 1.0139 3.4504 0.4150 0.0716 0.0193 0.4852 414: 0.4531 1.0140 3.4504 0.4152 0.0716 0.0193 0.4851 415: 0.4531 1.0140 3.4504 0.4152 0.0715 0.0194 0.4850 416: 0.4531 1.0141 3.4504 0.4151 0.0715 0.0194 0.4850 417: 0.4532 1.0141 3.4504 0.4153 0.0715 0.0194 0.4848 418: 0.4531 1.0141 3.4504 0.4151 0.0715 0.0194 0.4847 419: 0.4532 1.0142 3.4504 0.4152 0.0715 0.0194 0.4846 420: 0.4534 1.0141 3.4505 0.4151 0.0715 0.0194 0.4844 421: 0.4533 1.0141 3.4505 0.4149 0.0716 0.0194 0.4843 422: 0.4534 1.0140 3.4505 0.4150 0.0715 0.0193 0.4843 423: 0.4534 1.0139 3.4505 0.4149 0.0716 0.0193 0.4842 424: 0.4532 1.0139 3.4504 0.4149 0.0716 0.0193 0.4842 425: 0.4532 1.0140 3.4503 0.4151 0.0716 0.0193 0.4840 426: 0.4532 1.0141 3.4503 0.4152 0.0716 0.0194 0.4840 427: 0.4530 1.0142 3.4502 0.4153 0.0716 0.0193 0.4839 428: 0.4528 1.0143 3.4502 0.4152 0.0716 0.0194 0.4838 429: 0.4528 1.0143 3.4502 0.4152 0.0716 0.0194 0.4838 430: 0.4526 1.0144 3.4502 0.4150 0.0716 0.0194 0.4839 431: 0.4525 1.0144 3.4502 0.4147 0.0716 0.0193 0.4839 432: 0.4524 1.0145 3.4502 0.4145 0.0717 0.0193 0.4838 433: 0.4524 1.0145 3.4502 0.4145 0.0717 0.0193 0.4839 434: 0.4524 1.0144 3.4502 0.4146 0.0718 0.0193 0.4838 435: 0.4524 1.0144 3.4502 0.4145 0.0718 0.0193 0.4838 436: 0.4524 1.0144 3.4502 0.4146 0.0718 0.0193 0.4838 437: 0.4525 1.0144 3.4502 0.4147 0.0718 0.0193 0.4839 438: 0.4524 1.0145 3.4502 0.4146 0.0719 0.0193 0.4838 439: 0.4525 1.0146 3.4502 0.4148 0.0719 0.0193 0.4837 440: 0.4524 1.0146 3.4502 0.4146 0.0719 0.0192 0.4837 441: 0.4526 1.0146 3.4502 0.4147 0.0718 0.0192 0.4836 442: 0.4525 1.0147 3.4502 0.4146 0.0718 0.0192 0.4835 443: 0.4526 1.0148 3.4502 0.4148 0.0718 0.0192 0.4835 444: 0.4525 1.0149 3.4501 0.4149 0.0719 0.0192 0.4835 445: 0.4525 1.0149 3.4500 0.4152 0.0719 0.0191 0.4835 446: 0.4523 1.0150 3.4499 0.4153 0.0720 0.0191 0.4835 447: 0.4524 1.0150 3.4499 0.4153 0.0720 0.0191 0.4835 448: 0.4523 1.0150 3.4500 0.4149 0.0719 0.0191 0.4835 449: 0.4523 1.0151 3.4501 0.4145 0.0719 0.0191 0.4835 450: 0.4524 1.0150 3.4502 0.4141 0.0718 0.0191 0.4835 451: 0.4525 1.0150 3.4502 0.4141 0.0718 0.0192 0.4835 452: 0.4527 1.0150 3.4503 0.4141 0.0717 0.0192 0.4834 453: 0.4527 1.0150 3.4502 0.4138 0.0717 0.0192 0.4833 454: 0.4526 1.0151 3.4502 0.4137 0.0717 0.0191 0.4832 455: 0.4527 1.0152 3.4502 0.4139 0.0716 0.0191 0.4831 456: 0.4527 1.0152 3.4502 0.4141 0.0716 0.0191 0.4830 457: 0.4527 1.0151 3.4502 0.4143 0.0716 0.0191 0.4829 458: 0.4528 1.0152 3.4502 0.4145 0.0715 0.0192 0.4828 459: 0.4526 1.0153 3.4502 0.4144 0.0715 0.0191 0.4828 460: 0.4524 1.0153 3.4501 0.4142 0.0714 0.0192 0.4828 461: 0.4523 1.0154 3.4501 0.4140 0.0714 0.0192 0.4829 462: 0.4521 1.0156 3.4501 0.4139 0.0713 0.0192 0.4828 463: 0.4522 1.0156 3.4501 0.4137 0.0713 0.0192 0.4829 464: 0.4522 1.0157 3.4500 0.4136 0.0713 0.0191 0.4829 465: 0.4522 1.0156 3.4501 0.4134 0.0713 0.0191 0.4828 466: 0.4522 1.0156 3.4500 0.4131 0.0713 0.0191 0.4828 467: 0.4520 1.0156 3.4501 0.4128 0.0713 0.0191 0.4828 468: 0.4520 1.0156 3.4501 0.4126 0.0713 0.0191 0.4828 469: 0.4521 1.0158 3.4501 0.4128 0.0713 0.0191 0.4828 470: 0.4520 1.0158 3.4501 0.4129 0.0714 0.0191 0.4828 471: 0.4520 1.0159 3.4501 0.4127 0.0715 0.0191 0.4830 472: 0.4520 1.0159 3.4501 0.4127 0.0715 0.0191 0.4831 473: 0.4519 1.0159 3.4501 0.4125 0.0715 0.0190 0.4831 474: 0.4519 1.0159 3.4501 0.4124 0.0714 0.0190 0.4832 475: 0.4520 1.0160 3.4501 0.4123 0.0714 0.0190 0.4832 476: 0.4521 1.0160 3.4501 0.4124 0.0714 0.0190 0.4832 477: 0.4520 1.0159 3.4501 0.4123 0.0714 0.0190 0.4832 478: 0.4520 1.0159 3.4502 0.4122 0.0714 0.0190 0.4832 479: 0.4521 1.0159 3.4501 0.4124 0.0714 0.0190 0.4833 480: 0.4520 1.0159 3.4501 0.4122 0.0714 0.0190 0.4834 481: 0.4520 1.0160 3.4501 0.4119 0.0714 0.0190 0.4835 482: 0.4520 1.0160 3.4501 0.4119 0.0714 0.0190 0.4835 483: 0.4520 1.0160 3.4501 0.4121 0.0714 0.0190 0.4835 484: 0.4520 1.0159 3.4501 0.4123 0.0714 0.0190 0.4834 485: 0.4521 1.0160 3.4501 0.4125 0.0713 0.0190 0.4834 486: 0.4521 1.0160 3.4502 0.4123 0.0714 0.0190 0.4833 487: 0.4523 1.0160 3.4502 0.4123 0.0714 0.0190 0.4833 488: 0.4523 1.0160 3.4502 0.4121 0.0714 0.0190 0.4833 489: 0.4526 1.0160 3.4503 0.4121 0.0714 0.0190 0.4832 490: 0.4528 1.0160 3.4503 0.4124 0.0714 0.0190 0.4832 491: 0.4529 1.0160 3.4504 0.4122 0.0714 0.0190 0.4831 492: 0.4529 1.0161 3.4505 0.4120 0.0714 0.0190 0.4832 493: 0.4529 1.0160 3.4505 0.4118 0.0714 0.0190 0.4832 494: 0.4530 1.0160 3.4505 0.4116 0.0714 0.0190 0.4832 495: 0.4531 1.0160 3.4505 0.4116 0.0713 0.0190 0.4831 496: 0.4532 1.0160 3.4505 0.4116 0.0714 0.0191 0.4831 497: 0.4532 1.0160 3.4505 0.4118 0.0713 0.0191 0.4830 498: 0.4532 1.0160 3.4505 0.4119 0.0713 0.0191 0.4830 499: 0.4533 1.0160 3.4505 0.4121 0.0713 0.0191 0.4828 500: 0.4534 1.0160 3.4504 0.4122 0.0713 0.0191 0.4828 Calculating covariance matrix [====|====|====|====|====|====|====|====|====|====] 0:00:00 → creating full model... → pruning branches (`if`/`else`)... ✔ done → loading into symengine environment... ✔ done → compiling EBE model... make[1]: warning: jobserver unavailable: using -j1. Add '+' to parent make rule. make[1]: warning: jobserver unavailable: using -j1. Add '+' to parent make rule. ✔ done Error in .fitFun(.ret) : Mat::init(): mismatch between size of auxiliary memory and requested size Error in (function (data, inits, PKpars, model = NULL, pred = NULL, err = NULL, : Could not fit data. Error in .fitFun(.ret) : theta mismatch op_focei.ntheta 0, ntheta: 4 Error in (function (data, inits, PKpars, model = NULL, pred = NULL, err = NULL, : Could not fit data. Warning in (function (uif, data, est = NULL, control = list(), ..., sum.prod = FALSE, : Error calculating nlmixr object, return classic object Warning in (function (uif, data, est = NULL, control = list(), ..., sum.prod = FALSE, : Bounds are ignored in SAEM > > # even though you may have forgotten to add the NPDE, you can add it to the data.frame: > > f <- addNpde(f) add npde Error in .foceiThetaEtaParameters(fit) : Not compatible with requested type: [type=NULL; target=double]. Calls: addNpde ... .calcCwres -> .foceiPredIpredList -> .foceiThetaEtaParameters Execution halted * checking for unstated dependencies in ‘tests’ ... OK * checking tests ... Running ‘testthat.R’ OK * checking PDF version of manual ... OK * checking for non-standard things in the check directory ... OK * checking for detritus in the temp directory ... OK * checking for new files in some other directories ... OK * DONE Status: 1 ERROR See ‘/data/blackswan/ripley/R/packages/tests-devel/nlmixr.Rcheck/00check.log’ for details. Command exited with non-zero status 1 Time 3:59.18, 331.79 + 25.64