Istvan Miklos
Dr Istvan Miklos
Postdoctoral Researcher
miklos at stats.ox.ac.uk
+44 (0)1865 272860 (Department)
+44 (0)1865 272874 (Direct)
+44 (0)1865 272595 (Fax)
Research interests
Convergence of Markov chain Monte Carlo methods
Statistical alignment
Genome rearrangement
About my research
I have been working on modeling molecular evolution. My research focuses on insertion-deletion process (statistical alignment), on genome rearrangement and RNA folding.
I am partly involved in a project on multivariate biological data analysis, such as horseshoe effect in PCoA and statistical properties of presence-absence matrices.
I am interested in possible MCMC applications in bioinformatics (mainly Bayesian phylogenetic inferring) and ecology (generating null-distributions).
Selected publications
Csürös, M. & Miklós, I. (2006) A probabilistic model for gene content evolution with duplication, loss, and horizontal transfer Proceedings of RECOMB2006, LNBI 3909:206-220
Meyer, I.M. & Miklós, I. (2005) Statistical evidence for conserved, local secondary structure in the coding regions of eukaryotic mRNAs and pre-mRNAs. Nucleic Acids Research, 33(19) 6338-6348
Lunter, G.A., Miklós, I., Drummond, A., Jensen, J.L. & Hein, J. (2005) Bayesian Coestimation of Phylogeny and Sequence Alignment BMC Bioinformatics 6:83
Miklós, I., Novak, A., Dombai, B. & Hein, J. (2008) How reliably can we predict the reliability of protein structure predictions? BMC Bioinformatics 9:137
Miklós, I., Lunter, G. A. & Holmes, I. (2004) A 'long indel' model for evolutionary sequence alignment. Mol. Biol. Evol., 21(3):529-540
Full list of publications
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